Percutaneous absorption of chlorhexidine in neonatal cord care.
نویسندگان
چکیده
The percutaneous absorption of chlorhexidine during its routine use in topical antiseptic preparations used in umbilical cord care was investigated by determining plasma chlorhexidine concentrations at ages 5 and 9 days. These showed that percutaneous absorption of chlorhexidine occurred in preterm neonates treated with a 1% solution of chlorhexidine in ethanol, but not in term infants similarly treated, or in preterm infants treated only with a dusting powder containing 1% chlorhexidine and 3% zinc oxide.
منابع مشابه
A Randomized, Double-Blind Trial of Topical Breast Milk, Chlorhexidine, and Dry Cord Care on Umbilical Cord Bacterial Colonization in Premature Infants in NICU
Introduction: The purpose of this study was to compare the topical effect of breast milk, chlorhexidine, and dry cord care on the umbilical cord bacterial colonization in premature infants hospitalized in a neonatal intensive care unit. Methodology: This randomized controlled double-blinded trial was performed on premature infants admitted to the NICU of Valiasr Hospital, Birjand in 2016. The...
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متن کاملNewborn cord care practices in Haiti.
Newborn cord infections commonly lead to neonatal sepsis and death, particularly in low-resource countries where newborns may receive unhygienic cord care. Topical application of chlorhexidine to the newborn's cord has been shown to prevent infection. Such benefits may be particularly important in Haiti. We explored current cord care practices by conducting a qualitative study using five focus ...
متن کاملApplication of chlorhexidine to the umbilical cord after birth in low-income settings: two randomised controlled trials.
ed from El Arifeen S, Mullany LC, Shah R. The effect of cord cleansing with chlorhexidine on neonatal mortality in rural Bangladesh: a communitybased, cluster-randomised trial.. Lancet2012;379:1022–8. Source(s) of funding USA Agency for International Development. Study design Design: Community-based cluster-randomised trial. Allocation: Clusters were computer randomised by a statistician not in...
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BACKGROUND The World Health Organization recommends dry cord care for newborns but this recommendation may not be optimal in low resource settings where most births take place in an unclean environment and infections account for up to half of neonatal deaths. A previous trial in Nepal indicated that umbilical cord cleansing with 4.0% chlorhexidine could substantially reduce mortality and omphal...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 56 11 شماره
صفحات -
تاریخ انتشار 1981